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PATIENT Information

FASTER, SUSTAINED HEALING

Topical Wound Oxygen (TWO2®) is a non-invasive, clinically proven therapy for chronic and hard-to-heal wounds. It’s safe, comfortable, and can be provided at home under clinician guidance.

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Why Choose TWO2 Therapy

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Your health is our topmost priority

A unique 3-in-1 therapy

Chronic wounds are often hypoxic (low in oxygen). The Extremity Chamber (“Boot”) used with TWO2® delivers what healing tissue needs—oxygen, compression, and humidification—in one session. High-pressure topical oxygen feeds the wound surface, gentle non-contact compression helps mobilize fluids and reduce edema, and a fine mist maintains the ideal moisture balance for predictable healing.

Convenient & easy to use

TWO2® is designed for home comfort. Most patients relax, read, or watch TV during therapy. At the start, a NewCuraMedical clinical specialist sets up the equipment and shows you exactly how to run a session. Our Patient Guide provides step-by-step reminders, and if you need help later, our team is just a call away.

Compatible with dressings and TCCs

In many cases, your usual wound dressings—and even total contact casts (TCCs)—can stay on under the Extremity Chamber. Your doctor will confirm which dressings are compatible with TWO2® or if anything should be removed before treatment.

How Do I Get Started?

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Ask your doctor if TWO2® is the right therapy for your wound. Before starting, check with your provider and insurance company to confirm that your treatment costs are covered.

Getting Started

What to Expect


  • Before starting the therapy, use the bathroom, eat or grab a snack, and gather anything you want nearby—such as a TV remote, a book, your phone, and a glass of water.

  • You will need to sit or lie down for the duration of the therapy (60–90 minutes unless your doctor has prescribed otherwise).

  • There is NO SMOKING during therapy since oxygen is a fire hazard when near an open flame. Ensure fireplaces or candles are not lit in the room. Never use an open flame of any kind during treatment.

  • You may leave your wound dressings on unless your doctor instructs otherwise. The therapy can also work over a total contact cast (TCC).

  • You should not feel any pain during therapy. If you do, contact your doctor immediately.

Your questions answered

Follow your doctor’s prescription for how many therapy sessions you need each week. If you happen to miss a few, it’s okay to complete two sessions in one day to stay on track

At the beginning, a NewCuraMedical care specialist will visit your home to show you exactly how to use the TWO2® therapy. We’ll guide you step by step and remain available to answer any questions along the way.

No, If you feel pain during therapy, reach out to your NewCuraMedical representative first to check if simple adjustments can help. If the discomfort continues, be sure to contact your healthcare provider right away

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