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PATIENT Information

Heal Faster. Stay Healed

Hard-to-heal wound? TWO2® delivers topical oxygen therapy—safe, non-invasive, and clinically proven—so you can treat at home. #WoundCare #HealingAtHome

Partnering in Your Care

We’re committed to quality treatment—and getting you back to life.

Topical Wound Oxygen (TWO2) is a clinically supported option for chronic, hard-to-heal wounds. It’s safe, non-invasive and designed for comfort, including use in the convenience of your own home.

Why Choose TWO2 Therapy?


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A Unique 2-in-1 Therapy

All wounds require oxygen to heal. Chronic wounds often become hypoxic. The Multi-Patch delivers a high concentration and pressure of oxygen that diffuses deep into tissue, while built-in humidification maintains an ideal healing environment.

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Convenient & Easy-to-Use

TWO2 is designed around patients. Therapy can be taken at home while watching TV or reading. At start-up, an AOTI representative drops off the equipment, teaches you how to begin sessions, and support is only a phone call away if questions arise.

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Compatible with Dressings

In many cases your usual dressings can remain in place under therapy. Your provider will advise whether your current dressings are suitable for TWO2 or should be removed before treatment.


Getting Started & What to Expect


  • Before beginning, use the restroom, grab a snack, and collect anything you’ll want nearby during therapy (remote, book, phone, water, etc.).
  • Plan to sit or lie down for the entire session (typically 60–90 minutes unless your doctor prescribes otherwise).
  • NO SMOKING during therapy—oxygen is a fire hazard near open flame. Ensure fireplaces and candles are not lit and avoid any open flames during treatment.
  • You may keep wound dressings on unless your clinician has instructed otherwise.
  • Therapy should not be painful. If you feel pain, stop and contact your doctor immediately.
TWO2 Multi-Patch on lower back

Take control of your health today!